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Cleocin Gel

Active Ingredient: Clindamycin

Cleocin Gel is used for treating severe acne.

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Cleocin Gel is used for treating severe acne. Cleocin Gel is a topical lincomycin antibiotic. It works by killing sensitive bacteria that cause acne and reducing the amount of free fatty acids that irritate the skin surface.


Use Cleocin Gel as directed by your doctor.

  • Cleocin Gel is for topical use on the skin only.
  • Clean and dry the affected area. Cover the affected and surrounding area with a thin film of medicine.
  • Cleocin Gel works best if it is used at the same time each day.
  • Continue to use Cleocin Gel even if your condition improves. Do not miss any dose.
  • If you miss a dose of Cleocin Gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Cleocin Gel.


Store Cleocin Gel at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Protect from freezing. Keep Cleocin Gel out of the reach of children and away from pets.


Active Ingredient: Clindamycin phosphate.

Safety information

Do NOT use Cleocin Gel if:

  • you are allergic to any ingredient in Cleocin Gel or to lincomycin
  • you have Crohn disease, antibiotic-associated colitis, or ulcerative colitis.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Cleocin Gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a gastrointestinal (bowel) disease or diarrhea.

Some medicines may interact with Cleocin Gel. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Nondepolarizing muscle relaxants (eg, vecuronium) or succinylcholine because their actions and the risk of their side effects may be increased by Cleocin Gel
  • Erythromycin because it may decrease Cleocin Gels effectiveness.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cleocin Gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Cleocin Gel may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.
  • Several weeks may pass before you see improvement in your acne. Continue using Cleocin Gel for the full time recommended by your doctor.
  • Be sure to use Cleocin Gel for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Do not get Cleocin Gel in your eyes or on the inside of your nose or mouth. If you accidentally get the medicine in your eye, immediately flush with a large amount of cool tap water.
  • If severe diarrhea, stomach pain or cramping, or bloody stools develop during treatment or within several months after treatment with Cleocin Gel, check with your doctor or pharmacist right away. Do not treat it without first checking with your doctor.
  • Talk with your doctor before you use any other medicines or cleansers on your skin.
  • Cleocin Gel should not be used in children younger 12 years safety and effectiveness in these children have not been confirmed.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cleocin Gel while you are pregnant. It is not known if Cleocin Gel is found in breast milk. Do not breastfeed while taking Cleocin Gel.

Side effects

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Dryness itching oiliness or oily skin.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash hives itching difficulty breathing tightness in the chest swelling of the mouth, face, lips, or tongue) blood or mucus in stools bloody or severe diarrhea stomach cramps or pain swelling, redness, burning, or peeling of your skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.




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