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Active Ingredient: Losartan

Cozaar is used for treating high blood pressure alone or with other medicines.

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Cozaar is used for treating high blood pressure alone or with other medicines. It is used in certain patients to decrease the risk of stroke. It is used in certain patients to treat kidney problems caused by diabetes (diabetic nephropathy). Cozaar is an angiotensin II receptor blocker (ARB). It works by relaxing blood vessels. This helps to lower blood pressure.


Use Cozaar as directed by your doctor.

  • Take Cozaar by mouth with or without food.
  • Take Cozaar on a regular schedule to get the most benefit from it. Taking Cozaar at the same time each day will help you remember to take it.
  • Continue to take Cozaar even if you feel well. Do not miss any dose.
  • If you miss a dose of Cozaar, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Cozaar.


Store Cozaar at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cozaar out of the reach of children and away from pets.


Active Ingredient: Losartan potassium.

Safety information

Do NOT use Cozaar if:

  • you are allergic to any ingredient in Cozaar
  • you are in your second or third trimester of pregnancy
  • the patient is a child with severe kidney problems.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Cozaar. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are able to become pregnant
  • if you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue difficulty swallowing or breathing or hoarseness), including angioedema caused by treatment with an angiotensin-converting enzyme (ACE) inhibitor (eg, lisinopril)
  • if you have a history of heart problems (eg, heart failure), blood vessel problems, blood flow problems, liver or kidney problems, or diabetes
  • if you have a history of stroke or recent heart attack
  • if you are dehydrated or have low blood volume
  • if you have electrolyte problems (eg, high blood potassium levels, low blood sodium levels) or are on a low-salt (sodium) diet
  • if you are on dialysis or are scheduled to have major surgery.

Some medicines may interact with Cozaar. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood pressure may be increased
  • Potassium-sparing diuretics (eg, spironolactone, triamterene) or potassium supplements because the risk of high blood potassium levels may be increased
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, indomethacin, celecoxib) or rifampin because they may decrease Cozaars effectiveness
  • Lithium because the risk of its side effects may be increased by Cozaar.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cozaar may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Cozaar may cause dizziness, lightheadedness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Cozaar with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Cozaar may cause dizziness, lightheadedness, or fainting alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Cozaar may cause a serious side effect called angioedema. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes throat, or tongue difficulty swallowing or breathing or hoarseness.
  • Cozaar may not work as well to reduce the risk of stroke in black patients. Discuss any questions or concerns with your doctor.
  • Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your health care provider at once if any of these occur.
  • Check with your doctor before you use a salt substitute or a product that has potassium in it.
  • Tell your doctor or dentist that you take Cozaar before you receive any medical or dental care, emergency care, or surgery.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
  • If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.
  • Diabetes patients- This may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Lab tests, including blood pressure, blood electrolyte levels, and heart, kidney, or liver function, may be performed while you use Cozaar. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Cozaar should not be used in children younger 6 years safety and effectiveness in these children have not been confirmed.
  • Pregnancy and breast-feeding: Cozaar may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if Cozaar is found in breast milk. Do not breastfeed while taking Cozaar.

Side effects

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Diarrhea dizziness tiredness.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash hives itching difficulty breathing tightness in the chest swelling of the mouth, face, lips, or tongue hoarseness) change in the amount of urine produced chest pain dark urine difficulty swallowing fast, slow, or irregular heartbeat muscle pain or cramps severe or persistent stomach pain (with or without nausea or vomiting) symptoms of low blood pressure (eg, fainting, severe dizziness, lightheadedness) unusual bruising or bleeding vision changes yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.




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