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Active Ingredient: Oxybutynin

Oxytrol is used for relieving symptoms of bladder problems (urinary urgency, frequency, or leakage; loss of bladder control; and painful urination) in certain patients.

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Oxytrol (oxybutynin) reduces muscle spasms of the bladder and urinary tract.

Oxytrol transdermal skin patch is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased nighttime urination.

Oxytrol may also be used for purposes not listed in this medication guide.


Use Oxytrol exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Oxytrol comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

To use the Oxytrol patch, open the sealed pouch and remove the protective liner. Apply the transdermal patch to a clean, dry area on your stomach, hip or buttock. Avoid skin that is oily, irritated, or damaged. Avoid placing the patch on a skin area that will be rubbed by a waistband or tight clothing.

Press the Oxytrol patch onto the skin and press it down firmly with your fingers. Make sure the patch is well sealed around the edges. When properly applied, the patch should stay on while swimming or bathing.

Leave the Oxytrol patch in place and wear it for 3 to 4 days. You should change the patch twice per week. Each time you apply a new patch, choose a different skin area on your stomach, hip, or buttock. Do not apply a patch to the same skin twice within one week.

Try to change your Oxytrol patch on the same two days each week (such as every Sunday and Thursday). There is a calendar printed on the package of this medication to help you establish a steady patch-changing schedule.

If the patch falls off, try sticking it back on. If it does not stay on, replace it with a new one and wear it until your next regular patch-changing day. Do not change your schedule, even if you apply a new patch to replace one that has fallen off.

After removing an Oxytrol patch, fold it in half so it sticks together and throw it away in a place where children or pets cannot get to it.

Use baby oil or mild soap and water to remove any adhesive residue that stays on your skin. Avoid using harsh soaps, alcohol, nail polish remover, or other solvents that could irritate your skin.

The Oxytrol patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test. Keep the Oxytrol patch in its sealed pouch until you are ready to use it.


Adults: The usual dose is 5mg two or three times a day. This may be increased to a maximum of 5 mg four times a day to obtain a clinical response provided that the side effects are tolerated.

Elderly (including frail elderly):
The elimination half-life is increased in the elderly. Therefore, a dose of 2.5mg twice a day, particularly if the patient is frail, is likely to be adequate. This dose may be titrated upwards to 5mg two times a day to obtain a clinical response provided the side effects are well tolerated.

Children (under 5 years of age):
Not recommended.

Children (over 5 years of age):
Neurogenic bladder instability: the usual dose is 2.5mg twice a day. This dose may be titrated upwards to 5mg two or three times a day to obtain a clinical response provided the side effects are well tolerated. Nocturnal enuresis: the usual dose is 2.5mg twice a day. This dose may be titrated upwards to 5mg two or three times a day to obtain a clinical response provided the side effects are tolerated. The last dose should be given before bedtime.


Store this medicine at room temperature in a tightly-closed container, away from heat and light.


Active ingredient: Oxybutynin

Safety information

Do not use Oxytrol if you are allergic to oxybutynin, or if you have:

untreated or uncontrolled glaucoma

a blockage in your digestive tract (stomach or intestines) or

if you have decreased urination or are unable to urinate.

To make sure you can safely use Oxytrol, tell your doctor if you have any of these other conditions:


liver disease

kidney disease

myasthenia gravis

an enlarged prostate

an intestinal disorder, such as ulcerative colitis or

a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion.

FDA pregnancy category B. Oxytrol is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether oxybutynin passes into breast milk or if it could harm a nursing baby. Do not use Oxytrol without telling your doctor if you are breast-feeding a baby.

Important safety information:

Before using Oxytrol, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by oxybutynin.

Tell your doctor about all other medicines you use, especially:

atropine (Donnatal, and others)


dicyclomine (Bentyl)

glycopyrrolate (Robinul)

hyoscyamine (Anaspaz, Cystospaz, Levsin, and others)

mepenzolate (Cantil)

methantheline (Provocholine)

methscopolamine (Pamine)

propantheline (Pro-Banthine)

scopolamine (Transderm-Scop)

an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek) or

antifungal medicine such as itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), miconazole (Oravig), or voriconazole (Vfend).

This list is not complete and other drugs may interact with Oxytrol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Oxytrol: hives difficulty breathing swelling of your face, lips, tongue, or throat. Stop using Oxytrol and call your doctor at once if you have a serious side effect such as:

fever with hot, dry skin

uneven heart rate

pain or burning when you urinate

urinating less than usual or not at all or

severe itching, burning, or blistering that does not clear up within several hours after removing the skin patch.

Less serious Oxytrol side effects may include:

mild skin itching, burning, redness, or discoloration where a patch was worn

dizziness, drowsiness, weakness

dry eyes, blurred vision

dry mouth

warmth, tingling, or redness under your skin

nausea, vomiting, stomach pain

constipation or diarrhea

stuffy nose

back pain

feeling restless or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.




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